CDMO
Bokgoni ba R&D- Specialty
Ts'ebetso ea mokokotlo (Qeto le asymmetric synthesis, Catalyst le Enzyme)
Khetho ea liphetoho tsa enantiomers (Fetolela phetolo e se nang thuso hore e sebelisoe)
Nts'etsopele ea Ts'ebetso e sa tloloeng
Boitsebiso ba litšila (TOF, GC-MS, LC-MS, NMR)
Lipatlisiso tsa ho se hloeke ha Mutagenic
Patlisiso ea Elemental Impurity (ICP-MS)
Liketsahalo tse khethehileng
Li-Hydrazines, 1500L / methaka
Suzuki Coupling, 100L / methaka
Fischer-Indole Synthesis, 2000L / batch
Ullmann (Cu kapa Pd catalysis) Coupling, 500L / methaka
Phetoho ea Vilsmeier, 500L / batch
Likhatello tse phahameng:
* hydrogenation le hydroformylation: 1-2000L
Karabelo e tlase ea mocheso o tlase: (-80 ℃) 500L ~ 5000L / batch
Li-reagents tsa Organometallic:
* Alkyl lithium, 1500L / methaka, makhetlo a mangata (methyl lithium, n-butyl lithium, phenyl lithium)
* Grignard Reagent, 1500L / methaka
Production ya bokgoni
Bonyane mohala oa tlhahiso oa 20-35 GMP (o nang le sistimi ea 10 HVAC)
Bonyane li-Reactor tse 350-500 (Kakaretso: 350,000L-1000,000L)
Lisebelisoa tse Felletseng
Mocheso: Ho tloha ho -100 ℃ ho isa ho 200 ℃
Khatello: Ho tloha 50 Pa ho 35 atm
Lisebelisoa tsa li-Reactors: E hahiloe ka khalase, Ts'epe e sa beng le mabali, Halar Coated.
Boholo ba Reactors: Ho tloha ho 10L ho isa ho 8000L
